大阪梅田の発毛・育毛専門大阪AGA加藤クリニック

What’s the PRPGH

PRPGH Regenerative medicine is enhanced to improve healing power by using the tissue repair power of blood platelet factors contained in blood, encourages the hair growth.
PRPGH is autologous platelet rich plasma (PRP).
When life is injured and blood vessels are damaged, platelets induced in the endothelial cells of the damaged blood vessels aggregate to the injury part.
Then platelets cause degranulation in the process of blood coagulation, Various cytokines such as PDGF contained in these granules are released to promote wound healing.
The cells are activated by injecting of the growth factors taken from your own blood directly into the thinning hair part, it will improve the disorder of the hair cycle and promotes hair growth accordingly.

PDGF（Platelet derived growth factor）	Accelerate of cell proliferation/Vascularization/Activation effect of macrophage）
TGF-β	Accelerate of collagen production
VEGF	angiogenic activity
FGF（Fibroblast growth factor)	Tissue repair/ collagen production /Hyaluronic acid production
EGF(Epitherial growth factor)	Growth enhancing of epidermal cell/ Vascularization/ Accelerate of wound healing

What treatment is PRP therapy?

It is a treatment method that utilizes these effects, administers growth factors intensively to the thinning hair area.
Initially, it began with research on the promotion of wound healing　called trauma treatment, and treatment of intractable cutaneous ulcers.
It has many achievements in orthopedics and dentistry, these are used for scalp hair regeneration and promote hair growth in our clinic.
PRPGH Regenerative medicine has a good effect on AGA / FAGA / diffuse alopecia, but it may not be effective in the case of immune disease such as alopecia areata.

PRP therapy is used as a rejuvenation treatment using collagen hyperplasia, in the cosmetic dermatology department in recent years.
As humans get older, hormones called growth factors decrease.
Growth factors have functions such as promoting cell proliferation, angiogenesis, and promoting collagen production, and play a role in maintaining youth.
The decrease in growth factors inactivates cell division and causes all symptom of senility such as wrinkles and sagging.
As an effect of PRP treatment, effective for problems such as tightening pores, wrinkles, dents, sagging, and acne scars, and it can also regenerate the skin of the face, hands, neck.
There is almost no downtime such as swelling or internal bleeding, and small wounds created by injection can be covered with makeup, so it is a popular procedure these days.
※This clinic is a facility that has received a permission to provide PRP hair regeneration treatment to the Ministry of Health, Labor and Welfare.

Uses “French Shot U225” manufactured by Needle Concept

At our clinic, we use “French Shot U225 manufactured by Needle Concept” for PRP regenerative medicine, it was designed to hit an intradermal injection.
It is a high-quality device that can uniformly inject chemical liquid　into the optimum layer and has been developed and improved based on the aviation industry technology.
By automating injection time and injection pressure adjustment, it is possible to completely control the injection depth and injection volume, so injection can be performed more quickly and evenly than with injection by hand.
In addition, pain is reduced by using an extra-fine needle, you can get medical treatment　without use of an anesthetic.

Normal Hair Cycle

Hair is produced from the hair follicles in the skin, and human hair does not grow forever.
The repetition of hair regeneration and hair removal is called the hair cycle, and this hair cycle is divided into three stages.

Hair is produced by repeating these three stages.

PRP promotes anti-apoptotic effects that reduce the number of apoptosis (cell death) during this involuting phase of hair cycle and telogen.
In addition, IGF-1, which promotes neovascularization around hair follicles and proliferation of hair matrix cells, it also promotes the differentiation of hair root stem cells and prolongs the anagen phase of the hair cycle.

Treatment flow

Notes

• Don’t wash your hair on the day after surgery.
• Please refrain from intense exercise, sauna, rock bath, bathing, etc. on the day after surgery.
• Do not dye your hair, perm, or massage your scalp within 1 week before and after surgery.
• Try to avoid exposure to the sun before and after the operation.
• Very few people have allergies.
• he effect of treatment varies from person to person.

Risk and Side effect

• Allergies are less likely to occur, but in rare cases swelling and redness may continue for more than a week.
• It is not recommended for those who have lost their hair roots as it has no effect.
• There are individual differences in the proliferation of cells around the hair root, it may be difficult for the effect to appear.
• After injection, redness may continue for minutes to hours at the injection site.

Frequency of treatment

Basically, it is a treatment in combination with oral medicine, so the frequency is about once every 2 to 3 months. If you want to do more often, you can do it once a month.

Price

1time	143,000JPY(tax included)
3times	385,000JPY(tax included)
5times	605,000JPY(tax included)

Approval

Regenerative medicine provision plan permission for the purpose of skin regeneration using PRP

This clinic is a facility whose provision plan has been accepted by the Ministry of Health, Labor and Welfare.

Facility Number	FC5190032（Accepted 29th Aug, 2019）
Plan Number	PC5190068 (Accepted 4th Feb, 2020)